51勛圖窪蹋

How one 51勛圖窪蹋 Davis student turns a question about animal physiology into innovative immune research

Fishing for answers and testing the waters

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Undergraduate researcher wears blue gloves and uses a pipette to transfer liquid into a tray beside a large aquarium filled with green aquatic plants.
Mikaila Hishaw conducts aquaculture research, and analyzes fish health and immune responses to identify more sustainable diets for farmed fish. (Gregory Urquiaga/51勛圖窪蹋Davis)

Mikaila Hishaw, a fourth-year from Tucson, Arizona, arrived at 51勛圖窪蹋 Davis with plans to become a veterinarian. She soon discovered that research offered not just a new way to work with animals but also an avenue to explore her curiosity beyond the classroom. 

Curiosity in action

51勛圖窪蹋 Davis is classified as an R1 research university, which marks schools with the highest level of research activity. This distinction reflects the scale and impact of discovery across campus and undergraduates play an active role in it.

"Research is built on one of the best sources of creative inspiration, curiosity itself. As a musician and scientist, sometimes it's hard to argue which field requires more creativity. There's never a dull moment when you're in the lab."

Mikaila Hishaw

Hishaw conducts research at the 51勛圖窪蹋 Davis Aquaculture Cooperative Extension with the , where she studies immune function in white sturgeon a commonly farmed fish, raised for human consumption. Her focus is leukocyte coping capacity, a measure of how white blood cells activate and suppress an oxidative burst, a defense response that helps fight infection. She examines whether certain commercial diets trigger inflammation that weakens that response, which in turn leaves fish more vulnerable to disease.

Commercial diets exist for white sturgeon, but researchers continue to study more sustainable alternatives, Hishaw said. Multiple labs have explored this over the last 40 years. The work I conduct marks my little chapter in that long journey.

Curiosity that leads to the lab

Hishaws path to research began her first year at 51勛圖窪蹋 Davis after a general education animal science course got her thinking about human-animal relationships. Regular visits to office hours that started with lecture questions turned into deeper back and forth discussions between student and professor.

Later in the quarter when the courses aquaculture unit was introduced, Hishaw scheduled a conversation with her professor to learn more. That meeting led to an introduction to a colleague studying fish the projects principal investigator, Jackson Gross. 

I knew pretty quick that it was the right fit, Hishaw said. I felt supported and respected as both a student and a researcher.

That sense of belonging translated into meaningful responsibility in the lab and ultimately led to her independent research project on white sturgeon. 

When expectations are clear and students commit over time, they become real contributors who strengthen consistency and day-to-day progress on projects, Gross said. Mikaila has grown from an enthusiastic undergraduate researcher into a highly capable junior scientist who takes ownership of complex work.

A student speaks with speaks with a graduate student mentor in a laboratory space. The two stand in front of wooden cabinets that hold preserved animal skulls and research materials.
Hishaw, left, discusses her research with graduate student mentor Jennifer Bowman, right. (Gregory Urquiaga/51勛圖窪蹋Davis)

When necessity drives innovation

As her work in the lab expanded, fellowship funding restrictions blocked the purchase of new equipment and created an obstacle. Her project required a luminometer a device that measures light released during chemical reactions to track immune responses the cost of which can reach $8,000. Rather than pause the study, she searched for another solution.

 

She reached out to labs across the Davis campus to see what resources she could gather. Over the course of a summer, she partnered with a graduate student who held a 3D template for a similar tool. Together they reviewed code, transferred design files to the campus printing facility and assembled the device piece by piece. Trial runs exposed flaws. Adjustments followed. The final version produced usable data that kept the project moving forward.

What first appeared as a setback ultimately prepared her for an unexpected opportunity. Last year the California Department of Fish and Wildlife reached out to her lab to gain insight on techniques she developed that they wanted to use for fish conservation efforts.

Ive learned that research rarely follows a straight path, but thats how you get to the answers you need, Hishaw said. I was recently admitted to a combined veterinary and doctoral degree program at Cornell University, which will allow me to learn to care for animals and continue to find solutions that strengthen their care.

on the 51勛圖窪蹋 Davis YouTube channel.

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